I used Syrinscape for the first time in a game last night and I experienced much the same thing. The sound of a music file that I had uploaded sounded really bad — like it was been downsampled out the wazoo. Pretty distorted. I didn’t have time to mess with it in-session, but will be doing some tests today to see if I can figure out what’s going on. At first, I could get sounds to play reliably in the Online Player, so I downloaded the Mac Fantasy Player and that’s when I immediately, noticed the degraded sound quality.
On a more positive note, the user experience was for the most part really great. I was able to drift in and out of different scenes and transition them smoothly. That was a much better experience than the platform I was previously using. But the user interface on my Mac Mac Pro with Retina Display was so tiny, I could barely read the buttons and so forth. But managing the music in-session was really great.